Hematopoietic Cell Therapy
Hematopoietic stem cells (HSCs) have long been used to provide life-saving treatments for patients with malignant and non-malignant hematological disorders. While these treatments originally took the form of conventional bone marrow transplants, more recent breakthroughs in the field have provided cell therapy researchers with methods to correct genetic mutations in a patient鈥檚 own cells for autologous HSC transplantation.
We have compiled a selection of scientific resources to help you on your way in the complex and exciting field of hematopoietic cell therapy.
CRISPR-Cas9 Editing of Hematopoietic Stem and Progenitor Cells
In this webinar, Dr. Mark DeWitt will discuss the use of gene editing techniques for hematopoietic stem and progenitor cells HSPCs. Topics he will include are:
- Delivery of gene editing machinery to target cells
- Homology-directed repair for precise editing
- Culture conditions required for efficient editing
- Levels of correction needed for the treatment of monogenic disorders, such as sickle cell disease
Training Programs
On-Demand Course: Ancillary Materials
Learn about the translation pathway for cell and gene therapies and the ancillary material qualification process in this free, self-paced course.
On-Demand Course: Human Hematopoietic CFU Assay
Learn the key concepts of primary HSPC biology and how to successfully set up the colony-forming unit (CFU) assay in your own lab. Progress at your own pace through this free virtual course.
On-Demand Course: Applying the ISSCR Standards for Research
Learn to confidently apply the ISSCR Standards for Human Stem Cell Use in Research to your projects with this free virtual course developed in partnership with the International Society for Stem Cell Research (ISSCR).
*Neither the ISSCR nor the ISSCR Standards endorse any commercial products or services.
On-Demand Course: Introduction to STEMvision鈩 for Automated CFU Scoring Course
Learn how to standardize and automate the scoring of the CFU assay using STEMvision鈩 in this self-paced digital course. You鈥檒l gain access to lectures, step-by-step protocol videos, and a library of curated resources.
