Products for Pancreatic Research
Pancreatic Research
Derived from the ventral foregut endoderm, the pancreas is composed of an exocrine compartment that functions primarily to produce and secrete digestive enzymes and an endocrine compartment that functions to regulate glucose homeostasis. When grown with the appropriate signals, proliferative pancreatic cells form organoids representative of the pancreatic exocrine system; these organoids can then be maintained and manipulated in vitro. Differentiation of human embryonic cells (hESCs) or human induced pluripotent stem cells (hiPSCs) provide an additional model for studying pancreatic development and diseases such as diabetes.