Immune Tolerance
Immune tolerance is critical to prevent the development of autoimmune and inflammatory diseases. Although the concept of tolerance has long been established, researchers continue to uncover previously unknown mechanisms and therapeutic applications of immune tolerance.
Below is a collection of scientific resources for your immune tolerance research.
Regulatory T Cells
Ethan Shevach and Todd Davidson. This poster provides an updated overview of the development, phenotype and functions of regulatory T cells, in particular those subsets that express the transcription factor forkhead box P3 (FOXP3).
Get Your Free Copy >- Thomas Krausgruber, PhDDr. Thomas Krausgruber discusses his research on understanding the complex relationship between our immune system and the intestinal microenvironment
- How to Isolate Cells Directly from Whole Blood Using the EasySepâ„¢ Purple/Silver MagnetsHow to isolate highly purified immune cells directly from whole blood and takes as little as 20 minutes from start to finish
- Preparing a Polymorphonuclear Cell Fraction from Whole Blood using Ammonium Chloride LysisTechnical tip from our dedicated team of Product and Scientific Support specialists
- Selecting a Protocol on the RoboSepâ„¢-SBasic overview on how to use and maintain your RoboSepâ„¢-S; steps involved to select a cell separation protocol
- Cell Isolation Directly from Whole Blood without RBC Lysis or Centrifugation: EasySepâ„¢ DirectIntroduction to the EasySepâ„¢ Direct immunomagnetic cell separation platform
- How to Isolate PBMCs from Whole Blood Using the SepMateâ„¢ PBMC Isolation Tubes: 15-Minute ProtocolEasy and rapid procedure for isolating peripheral blood mononuclear cells (PBMCs) from whole blood or bone marrow using the unique SepMateâ„¢ PBMC isolation tubes
- Isolate Multiple Cell Types from a Single Sample with Sequential IsolationSequential separation, for higher recovery of purified cells from limited sample size and isolation of multiple cell types, is ideal for chimerism analysis
- Using Cell Density Gradients to Optimize Your Cell IsolationsRosetteSepâ„¢, a unique immunodensity cell isolation platform, isolates highly purified cells by density gradient centrifugation without columns or magnets
- Unloading the RoboSepâ„¢-S CarouselBasic overview on how to use and maintain your RoboSepâ„¢-S; steps to unload the instrument after a cell separation run has been completed
- How to Isolate Cells with EasySepâ„¢ Column-Free Cell Separation TechnologyIsolation of human CD4+ T cells by negative selection using EasySepâ„¢ to separate highly purified cells in as little as 8 minutes
- Improving Cell Recovery with EasySepâ„¢ Negative Selection KitsTechnical tip from our dedicated team of Product and Scientific Support specialists
- Isolate Cells with a Simple Pour-Off: EasySepâ„¢ Cell Separation TechnologyLearn how to perform the EasySepâ„¢ pour-off