Immune Tolerance
Immune tolerance is critical to prevent the development of autoimmune and inflammatory diseases. Although the concept of tolerance has long been established, researchers continue to uncover previously unknown mechanisms and therapeutic applications of immune tolerance.
Below is a collection of scientific resources for your immune tolerance research.
Regulatory T Cells
Ethan Shevach and Todd Davidson. This poster provides an updated overview of the development, phenotype and functions of regulatory T cells, in particular those subsets that express the transcription factor forkhead box P3 (FOXP3).
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Isolate Cells from Whole Blood without Columns or Magnets: RosetteSepâ„¢ Immunodensity Cell SeparationDescribes statistical models that can be used to estimate the probability of monoclonality for limiting dilution cloning and semi-solid cloning -
How to Isolate Cells with EasySepâ„¢ Column-Free Cell Separation TechnologyIsolation of human CD4+ T cells by negative selection using EasySepâ„¢ to separate highly purified cells in as little as 8 minutes -
How EasySepâ„¢ Magnetic Cell Separation Technology Works: Fast and Easy Cell IsolationEasySepâ„¢ technology, a fast and easy immunomagnetic cell separation technology that allows you to isolate virtually any cell types from a variety of sample sources in as little as 8 minutes -
How SepMateâ„¢ PBMC Isolation Tubes Work: From Whole Blood to PBMCs in 15 MinutesSepMateâ„¢, an innovative tube that enables consistent and hassle-free peripheral blood mononuclear cell (PBMC) isolation, for fast and easy PBMC isolation from whole blood in just 15 minutes using density gradient centrifugation -
Polishing the RoboSepâ„¢-S Tip HeadBasic overview on how to use and maintain your RoboSepâ„¢-S; how to polish the tip head -
Before Starting a Run on RoboSepâ„¢-SBasic overview on how to use and maintain your RoboSepâ„¢-S; steps to follow before starting a cell separation run -
Selecting a Protocol on the RoboSepâ„¢-SBasic overview on how to use and maintain your RoboSepâ„¢-S; steps involved to select a cell separation protocol -
Loading the RoboSepâ„¢-S Carousel and Starting a RunBasic overview on how to use and maintain your RoboSepâ„¢-S; steps to load the instrument with samples and reagents and start a cell separation run -
Unloading the RoboSepâ„¢-S CarouselBasic overview on how to use and maintain your RoboSepâ„¢-S; steps to unload the instrument after a cell separation run has been completed -
Removing the RoboSepâ„¢-S Carousel for CleaningBasic overview on how to use and maintain your RoboSepâ„¢-S; how to remove the carousel for cleaning -
RoboSepâ„¢-S ShutdownBasic overview on how to use and maintain your RoboSepâ„¢-S; how to shutdown the instrument if no more runs are planned for the day -
Automate Cell Isolation for Up to 16 Samples with the RoboSepâ„¢-16 Cell Separation InstrumentFeatures and benefits of using the fully automated cell isolation platform RoboSepâ„¢-16 which allows you to efficiently isolate cells from up to 16 samples simultaneously
