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³§°Õ·¡²Ñ±è°ù±ð±èâ„¢ Tissue Dissociator | Automated Tissue Dissociation for High-Quality Single-Cell Suspensions

Research and development in various fields, including oncology and immunology, rely on single-cell suspensions for use in applications such as flow cytometry and single-cell sequencing. Effective tissue dissociation methods are needed to generate single-cell suspensions with high viability. However, conventional manual dissociation methods can be labor-intensive, inconsistent, and prone to variability, all of which can negatively affect reproducibility and data accuracy.

To address these challenges, we developed the ³§°Õ·¡²Ñ±è°ù±ð±èâ„¢ Tissue Dissociation System—an automated solution that standardizes and streamlines the dissociation process. With built-in temperature control, modular scalability, and an intuitive interface, ³§°Õ·¡²Ñ±è°ù±ð±èâ„¢ ensures efficient, reproducible, and high-yield single-cell suspensions from a wide range of solid tissues while preserving epitope integrity and cell functionality.

Why Use ³§°Õ·¡²Ñ±è°ù±ð±èâ„¢?

  • Standardize tissue dissociation with automation for consistent, reproducible results.
  • Obtain high numbers of viable single cells with preserved functionality for downstream applications.
  • Ensure optimal sample processing for various sample types and applications with built-in temperature control from 4 to 37°C.
  • Choose from a 4-sample, 8-sample, or 12-sample system—scaling seamlessly to meet increasing throughput needs while maintaining efficiency.
  • Use validated º£½ÇÆÆ½â°æ protocols or create your own to adapt ³§°Õ·¡²Ñ±è°ù±ð±èâ„¢ to different tissue types and experimental needs.

Seamless Integration into Your Workflow

³§°Õ·¡²Ñ±è°ù±ð±èâ„¢ integrates with º£½ÇÆÆ½â°æ Technologies’ tissue processing and cell isolation solutions, enabling an end-to-end workflow. Resultant cell suspensions can be used with ·¡²¹²õ²â³§±ð±èâ„¢ for column-free cell isolation; ±õ³¾³¾³Ü²Ô´Ç°ä³Ü±ô³Ùâ„¢ immune cell culture media, activators, and supplements; or other º£½ÇÆÆ½â°æ reagents to maximize cell purity and recovery.

Figure 1. ³§°Õ·¡²Ñ±è°ù±ð±èâ„¢ Tissue Dissociation Workflow

The ³§°Õ·¡²Ñ±è°ù±ð±èâ„¢ Tissue Dissociator enables efficient processing of various tissue types, including mouse brain, liver, lung, spleen, and tumors. In this workflow, a tissue is placed into the ³§°Õ·¡²Ñ±è°ù±ð±èâ„¢ sample tube and processed using the ³§°Õ·¡²Ñ±è°ù±ð±èâ„¢ Tissue Dissociator. Depending on the selected protocol—dissociation or homogenization—the resulting sample will either be a single-cell suspension or nucleic acids. The processed sample can then be used for various downstream applications, such as cell isolation, activation, culture, and analysis.

Related Resources

Brochure
Elevate Tissue Dissociation with ³§°Õ·¡²Ñ±è°ù±ð±èâ„¢