T Cell Therapy
Adoptive T cell therapy has brought excitement to immuno-oncology research and hope to cancer patients who are out of treatment options. The most popular form of T cell for therapy are chimeric antigen receptor (CAR) T cells. These cells are engineered to express a synthetic transmembrane receptors containing the variable domain of an antibody to redirect their specificity to recognize and eliminate cancer cells upon infusion in patients.
Below is a collection of scientific resources for your T cell therapy research.
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Rational Combination of Cancer Therapies with PD1 Axis Blockade
This free wallchart from Nature Reviews Cancer and Nature Reviews Immunology provides a detailed overview of cancer-immune pathways, combination immunotherapies, and more.
Get Your Free Copy >- Optimized Workflows for High-Efficiency Genome Editing in Stem and Primary Cell TypesCRISPR-Cas genome editing in cell culture systems is a powerful technique for disease modeling and the development of cellular therapies. Compared to work with immortalized cell lines, genome editing of stem and primary cells presents unique challenges, including issues related to efficient delivery and expression of CRISPR machinery, clonogenicity, and cytotoxicity. In this webinar, our in-house expert, Dr. Ashley Watson, discusses optimized workflows for CRISPR-Cas9 genome editing in human pluripotent stem cells and primary T cells.
- How EasySepâ„¢ Magnetic Cell Separation Technology Works: Fast and Easy Cell IsolationEasySepâ„¢ technology, a fast and easy immunomagnetic cell separation technology that allows you to isolate virtually any cell types from a variety of sample sources in as little as 8 minutes
- How to Isolate Cells with EasySepâ„¢ Column-Free Cell Separation TechnologyIsolation of human CD4+ T cells by negative selection using EasySepâ„¢ to separate highly purified cells in as little as 8 minutes
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