T Cell Therapy
Adoptive T cell therapy has brought excitement to immuno-oncology research and hope to cancer patients who are out of treatment options. The most popular form of T cell for therapy are chimeric antigen receptor (CAR) T cells. These cells are engineered to express a synthetic transmembrane receptors containing the variable domain of an antibody to redirect their specificity to recognize and eliminate cancer cells upon infusion in patients.
Below is a collection of scientific resources for your T cell therapy research.
Rational Combination of Cancer Therapies with PD1 Axis Blockade
This free wallchart from Nature Reviews Cancer and Nature Reviews Immunology provides a detailed overview of cancer-immune pathways, combination immunotherapies, and more.
Get Your Free Copy >- Advances in Point-of-Care Cell Engineering—What Are You Feeding Your CAR T Cells?In this webinar, Dr. Julian J. Lum discusses key factors to consider when choosing metabolic assays and how they can be used to assess cell function. Additionally, he discusses the metabolic characteristics of different commercially available cell culture media formulations as well as the importance of assessing the array of media products and their impact on metabolism.<br><br>This webinar is part of the “Translational T Cell Talks: Scaling for the Future†event hosted in collaboration with Scientist.com on June 11, 2024. <a href="/translational-t-cell-talks-2024">View the rest of the talks and read the Q&A transcripts.</a>
- Streamline Your Mouse T Cell Research from Isolation to ExpansionT cells are used in a range of research areas, including fundamental biological research, cellular therapy development, disease modeling, and drug discovery. Harnessing the power of T cells for these applications often starts with animal models. Watch this on-demand webinar to discover tools to support every stage of your mouse T cell workflow, from sample processing to cell isolation, activation, differentiation, and analysis.
- Combining CAR T Cells with STING Agonists to Fight Solid TumorsIn this webinar, Dr. Uslu describes how IMSA101 enhances CAR T function through STING agonist-induced IL-18 secretion and how these findings lay the foundation for advancing the combinatorial approach into a clinical setting.<br><br>This webinar is part of the “Translational T Cell Talks: Scaling for the Future†event hosted in collaboration with Scientist.com on June 11, 2024. <a href="/translational-t-cell-talks-2024">View the rest of the talks and read the Q&A transcripts.</a>
- Next-Generation Cell Isolation Solutions for T Cell Therapy ResearchJoin this talk, presented by Dr. Amanda Durkin and Q&A guest Dr. Frann Antignano, to learn about º£½ÇÆÆ½â°æâ€™s cell isolation solutions for fast and easy T cell isolation. This presentation will also focus on large-scale research strategies by introducing our new mobilized leukopaks and feature the Easy 250 EasySepâ„¢ Magnet—a scalable and efficient system for manual column-free isolation.<br><br>This webinar is part of the “Translational T Cell Talks: Scaling for the Future†event hosted in collaboration with Scientist.com on June 11, 2024. <a href="/translational-t-cell-talks-2024">View the rest of the talks and read the Q&A transcripts.</a>
- Tools for Optimizing Human Immune Cell ResearchObtaining consistent and reliable results when culturing immune cells can be challenging. Watch this webinar to discover how to obtain high yields of functional T cells, NK cells, B cells, dendritic cells, and macrophages for your research applications. The speaker, Evan Karas, also explains how to expand primary T cells without feeders or serum.
- Accelerating T Cell Therapy ResearchObtaining high yields of viable engineered T cells for cell therapy research and immunotherapy development can be challenging. Lengthy and inefficient processes for cell isolation, cell culture, and gene transfer can cause delays and prevent scientists from reaching their goals. Watch as Drs. Sneha Balani and Angela Zhang discuss best practices and innovative technologies for T cell therapy research.
- Lost in Translation - Moving Your Research to Clinical TrialsThis webinar describes steps and considerations involved in translating research to the clinic.
