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Neurological Disease Modeling

Due to the difficulty in obtaining human brain tissue for experimental studies, animal models have traditionally been popular tools for neurological disease modeling and therapeutic evaluation. In recent years, however, researchers have begun using induced pluripotent stem cells (iPSCs) to generate more representative models for studying human neurological disease. These iPSC-based models, including iPSC-derived neurons, glia, neural organoids, and co-cultures, hold tremendous potential for drug discovery applications and studying human neurological disease. Researchers can now generate patient-specific differentiated cell types, bridging the translational gap between studies using animal models and clinical research.

We’ve created these resources to help you with your research in neurological disease modeling and drug discovery, and to give you a taste of what others are doing in the field.

Training Programs

Applying the ISSCR Standards for Research

On-Demand Course: Applying the ISSCR Standards for Research

Learn to confidently apply the ISSCR Standards for Human Stem Cell Use in Research to your projects with this free virtual course developed in partnership with the International Society for Stem Cell Research (ISSCR).

*Neither the ISSCR nor the ISSCR Standards endorse any commercial products or services.

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