Mammary Research
The mammary gland is a dynamic organ that undergoes extensive morphological changes through development, puberty, pregnancy, lactation and involution. Maintenance of the mammary epithelium during all of these stages is via mammary stem/progenitor cells.
Below is a collection of resources to support your mammary research.
Mammary Stem Cells and Breast Cancer
This mini-review describes the organization of mammary epithelium, identification of mammary stem and progenitor cells, phenotypic profiling and cell culture methods for mammary epithelial cells, as well as the current understanding of mammary stem cells in the context of breast cancer.
Read More >- SnapShot: Breast CancerOverview of signaling pathways, commonly mutated genes and breast cancer subtypes
- Small Molecules, Big Impact in Cancer ResearchOverview of signaling pathways and small molecules in cancer research
- Bright Ideas Podcast: ALDH in Breast Cancer Treatment ResponseTune in to this 10-minute Bright Ideas With ALDEFLUORâ„¢ podcast to learn about a recent publication that demonstrated a key role for ALDH in breast cancer treatment response
- Flow Cytometry Analysis of ALDH Bright Cells with the ALDEFLUORâ„¢ Assay KitThe ALDEFLUORâ„¢ fluorescent reagent system has supported over 200 publications to date
- How to Detect and Isolate Normal and Cancer Stem Cells Based on ALDH Activity with ALDEFLUORâ„¢An innovative, antibody-free system to rapidly identify stem and progenitor cells of several tissue types, including a variety of cancer stem cells
- Introducing EpiCultâ„¢-C MediumThis medium is fully defined and BPE-free and it supports robust growth of human luminal epithelial and myoepithelial mammary cells
- Optimization of ALDEFLUORâ„¢ ProtocolLearn how º£½ÇÆÆ½â°æ Technologies' scientists doubled the signal strength in mammary epithelial cells with a few simple protocol modifications using ALDEFLUORâ„¢ to detect Aldehyde Dehydrogenase bright (ALDHbr) cells
- Culture Mammospheres and Tumorspheres with the MammoCultâ„¢ MediumVideo discusses MammoCultâ„¢, a medium that supports the growth of primary human mammary epithelial cells as well as numerous breast cancer cell lines
- How to Count 3D Sphere Cultures (Mammospheres, Neurospheres, Cancer Spheroids, and PSC Aggregates)Technique for counting 3D sphere cultures, such as mammospheres, neurospheres, or cancer spheroids