Cell Sourcing and In Vitro Models
High-quality cells are the foundation of reliable research. When combined with optimized cell culture media and tools, they enable the development of in vitro models that help researchers study human biology in controlled, reproducible systems. Human cell-based models are becoming increasingly important for improving translational relevance and generating data that operationalize new approach methodologies (NAMs) and complement insights from animal models. In drug discovery, these models can support disease-relevant research, assay optimization, and predictive toxicology workflows, but their performance depends on the quality and consistency of the biological inputs and culture systems used to create them. As a result, cell source, model format, and standardization are critical for generating reliable data that can inform decision-making.
Backed by more than 30 years of experience in in vitro model development, º£½ÇÆÆ½â°æ provides high-quality, ethically sourced human primary cells, human pluripotent stem cells (hPSCs) and hPSC-derived differentiated cells, and practical resources to support standardized model development. Researchers can use these cell sources to generate in vitro tissue models in a range of culture formats, including 2D monolayer cultures, air-liquid interface models, and organoids.
Human Induced Pluripotent Stem Cell-Based Solutions
hPSCs, including human induced pluripotent stem cells (hiPSCs), enable researchers to generate diverse lineage-specific cell types and organoids for human-relevant in vitro model systems that can be used to generate human-relevant insights. Their capacity for self-renewal and functional differentiation, as well as their compatibility with genome editing, makes hiPSCs a versatile tool for modeling disease mechanisms and supporting preclinical applications such as drug screening, and regenerative medicine research. Start your research confidently with highly characterized, ethically sourced hiPSC lines, hiPSC-derived cells, and organoids developed in accordance with the . To further support hPSC-based workflows, º£½ÇÆÆ½â°æ also provides STEMdiffâ„¢ Pluripotent Stem Cell Differentiation Media for reproducible hPSC differentiation. With the right starting materials, you can focus on innovation and discovery instead of troubleshooting cell quality issues.
Human Primary Cell-Based Solutions
Human primary cell-based solutions help researchers build more physiologically relevant in vitro systems by using cells that retain key characteristics of their tissue of origin. This makes them valuable for applications such as disease modeling, cell-based assays, and toxicity testing, particularly when native biology and donor variability are important.
Human primary cells are cells isolated directly from human tissues, including blood and bone marrow, using enzymatic or mechanical methods. Choose ready-to-use fresh or cryopreserved cells, including mononuclear cells (MNCs), purified immune cells, or CD34+ stem and progenitor cells isolated from blood or bone marrow, and begin experiments when you are ready.* As a reliable supplier of human primary cells, and cell culture media, º£½ÇÆÆ½â°æ supports researchers in developing more biologically relevant workflows for model development, assay setup, and downstream decision-making, including applications involving commercial microphysiological systems and other advanced in vitro models. To try human primary cell products in your workflow, fill out this form to request information about introductory offers.
*Certain products are only available in select territories. Please contact your sales representative or the Product & Scientific Support team at techsupport@stemcell.com for further information.
Explore the tissue-specific learning centers below to learn more about building human in vitro tissue models, or request a seminar to see how in vitro models can help strengthen your drug discovery pipeline.