Organoids in Drug Discovery
Predictive methods are needed to increase the chance of success in your drug programs before clinical trials. Organoids are a beneficial tool in drug discovery and toxicity testing, aiding target discovery, validation, and pre-clinical testing. Organoid models provide a more physiologically relevant cellular composition and tissue structure than standard 2D models, with increased accuracy and higher throughput. Additionally, patient-derived organoids can be used to predict drug toxicity and efficacy, allowing you to make precise and confident decisions to advance your drug candidates.
Learn how organoids can help your drug-discovery workflow below.
Interview: The Role of Organoids and Organ-On-A-Chip Systems in Drug Discovery
Drs Bas Trietsch, Chief Technology Officer at MIMETAS, and Jenna Moccia, Director of Product Management at ƽ Technologies, discuss the challenges that lead pharma companies to adopt advanced in vitro models, such as organoids and organ-on-a-chip, and the benefits they see after incorporating these systems in their research.
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Advancing Organoid Models: Introducing New Capabilities for Intestinal and Hepatic ResearchIn this webinar, Riya Sharma, Senior Scientist at ƽ Technologies, introduces new tools and workflows designed to support advanced organoid research in intestinal and hepatic biology. She presents IntestiCult™ Plus Organoid Growth Medium, a next-generation solution that enables modular, serum-free expansion and differentiation of human intestinal organoids with enhanced regional and cell-type diversity confirmed by single-cell RNA sequencing. The webinar also features STEMdiff™ Hepatic Organoid Media, optimized for the derivation and maturation of hepatic organoids from hPSC-derived hepatocyte-like cells, and Organoid Culture Plates that improve uniformity, imaging, and automation compatibility.<br><br>As a supporter of, and participant in, ISSCR’s 2025 Annual Meeting, we share with you our presentation at ISSCR 2025. This presentation does not represent an endorsement from or support of the ISSCR. -
Dynamic Modeling in OrganoidsLearn more about organoid applications for studying human health -
Initiating Intestinal Organoid Differentiation from Single-Cell hPSCs Using STEMdiff™<meta property="og:title" content="Using Single-Cell hPSCs for Intestinal Organoid Differentiation"/> <meta property="og:description" content="Want more control over your PSC cell populations for downstream differentiation? Check out our new protocol to learn how to prepare single cells for the use in intestinal organoid differentiations."/> <meta property="og:image" content="https://cdn.stemcell.com/media/images/social/PR00084-Intestinal-Organoid-Diff.jpg"/> <meta name="twitter:title" content="Using Single-Cell hPSCs for Intestinal Organoid Differentiation"/> <meta name="twitter:description" content="Want more control over your PSC cell populations for downstream differentiation? Check out our new protocol to learn how to prepare single cells for the use in intestinal organoid differentiations."/> <meta name="twitter:card" content="summary_large_image"/> <meta name="twitter:site" content="@ƽTech"/> <meta name="twitter:image" content="https://cdn.stemcell.com/media/images/social/PR00084-Intestinal-Organoid-Diff.jpg"/> -
Building Three-Dimensional Human Brain OrganoidsOverview of brain organogenesis and the applications of brain organoids in studying the development and maturation of the nervous system -
Nature Research Round Table: The Promise of Organoid MedicineDr. Takanori Takebe discusses how organoids can be used to expand clinical applications of diseases and disorders. Dr. Takebe is an Assistant Professor at the Cincinnati Children’s Hospital Medical Center and Associate Professor at Yokohama City University. <br><br> This presentation was part of a Round Table series titled “Advances in Organoid Applications”, organized in partnership with Nature Research and held at the Springer Nature headquarters in London, UK in June 2019. There, global organoid experts gathered to discuss the current state of the technology. Core discussions centered around protocol standardization, translation into patient care, nomenclature, and understanding what questions a given organoid culture can and can’t answer.
