Neural Stem Cells
Neural stem cells have been identified in nearly all regions of the developing mouse, rat and human central nervous system (CNS) and in specialized neurogenic regions of the mature CNS.The identification of CNS-resident NSCs and the discovery that adult somatic cells from mouse and human can be reprogrammed to a pluripotent state, and then directed to differentiate into neural cell types, has opened the door to new therapeutic avenues aimed at replacing lost or damaged CNS cells.
We've created these resources to support your neural stem cell research.
Neural Stem Cell Culture Systems - Neurosphere vs. Adherent Monolayer Culture
This webinar provides an overview of the neurosphere and adherent monolayer methods to culture neural stem and progenitor cells. Technical aspects and details associated with performing each of the culture methods are discussed. In addition, data comparing the two methods is presented.
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Workflows for Culturing Primary-Derived Neural Stem and Progenitor CellsNeuroCultâ„¢, developed to support the proliferation of NSCs in neurosphere suspension cultures, is also fully compatible with adherent culture systems -
How to Detect and Isolate Normal and Cancer Stem Cells Based on ALDH Activity with ALDEFLUORâ„¢An innovative, antibody-free system to rapidly identify stem and progenitor cells of several tissue types, including a variety of cancer stem cells -
How to Cryopreserve NeurospheresBank neural stem and progenitor cells from patient samples or fresh animal tissue for downstream experiments on self-renewal, differentiation potential, or pathology -
SnapShot: Glioblastoma MultiformeOverview of the key concepts and mechanisms in glioblastoma multiforme biology -
Directed Differentiation of Pluripotent Stem CellsStrategies for differentiating ES and iPS cells into ectoderm, endoderm or mesoderm -
Building Three-Dimensional Human Brain OrganoidsOverview of brain organogenesis and the applications of brain organoids in studying the development and maturation of the nervous system -
Neural Stem CellsOverview of the types of NSCs and their potential use as therapeutic agents for disease
