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Pluripotent Stem Cell-Derived Therapies

Each year, more human pluripotent stem cell(hPSC)-derived therapies move toward the clinic, which is why it’s important to stay up-to-date with the latest advancements in the field. Whether you’re just about to start your next project or are well on your way to clinical trials, the big picture of clinical translation in terms of patient safety, cell quality, and physiological relevance should always be top of mind.

Below is a collection of scientific resources to highlight the exciting potential of hPSC-derived therapies.

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  1. Differentiation of Human Pluripotent Stem Cells to Immune Cells for Cell Therapy Development
    Differentiation of Human Pluripotent Stem Cells to Immune Cells for Cell Therapy Development
    In this webinar, Diana Golubeva, Scientist in the Immunology group at º£½ÇÆÆ½â°æ Technologies, presents a robust, scalable platform for differentiating human pluripotent stem cells (hPSCs) into functional immune cells for allogeneic cell therapy development. By integrating TeSRâ„¢-AOF 3D for xeno-free suspension culture and STEMdiffâ„¢ Hematopoietic-EB reagents, the protocol enables efficient, high-yield generation of CD34⺠hematopoietic stem and progenitor cells (HSPCs). These HSPCs serve as a foundation for downstream differentiation into lymphoid lineages—including natural killer (NK), T, and B cells—using STEMdiffâ„¢ and StemSpanâ„¢ kits, all optimized for feeder-free workflows and scalable bioreactor formats.<br><br>As a supporter of, and participant in, ISSCR’s 2025 Annual Meeting, we share with you our presentation at ISSCR 2025. This presentation does not represent an endorsement from or support of the ISSCR.
  2. Quality by Design: Reagents and Support for hPSC-Derived Cell and Gene Therapies
    Quality by Design: Reagents and Support for hPSC-Derived Cell and Gene Therapies
    Each year, more human pluripotent stem cell-derived (hPSC-derived) therapies move towards the clinic, and º£½ÇÆÆ½â°æ is committed to supporting researchers from discovery to clinical application. In this Innovation Showcase from ISSCR 2021, Lynn Csontos will demonstrate how we build quality into our products, processes, and policies to support your project timing, product quality, and overall vision. Kimberly Snyder will then present data that shows how TeSRâ„¢-AOF, a novel animal origin-free (AOF) hPSC maintenance medium, can support optimized cell quality, improved performance and reproducibility across all cell lines.
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