Pluripotent Stem Cell-Derived Therapies
Each year, more human pluripotent stem cell(hPSC)-derived therapies move toward the clinic, which is why it’s important to stay up-to-date with the latest advancements in the field. Whether you’re just about to start your next project or are well on your way to clinical trials, the big picture of clinical translation in terms of patient safety, cell quality, and physiological relevance should always be top of mind.
Below is a collection of scientific resources to highlight the exciting potential of hPSC-derived therapies.
In this Innovation Showcase presentation, Lynn Csontos demonstrates how º£½ÇÆƽâ°æ can support your project timing, product quality, and overall vision by building quality into our products, processes, and policies. Kimberly Snyder then presents data showing how TeSRâ„¢-AOF, a novel animal origin-free (AOF) hPSC maintenance medium, supports optimized cell quality, improved performance, and reproducibility across all cell lines.
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Differentiation of Human Pluripotent Stem Cells to Immune Cells for Cell Therapy DevelopmentIn this webinar, Diana Golubeva, Scientist in the Immunology group at º£½ÇÆƽâ°æ Technologies, presents a robust, scalable platform for differentiating human pluripotent stem cells (hPSCs) into functional immune cells for allogeneic cell therapy development. By integrating TeSRâ„¢-AOF 3D for xeno-free suspension culture and STEMdiffâ„¢ Hematopoietic-EB reagents, the protocol enables efficient, high-yield generation of CD34⺠hematopoietic stem and progenitor cells (HSPCs). These HSPCs serve as a foundation for downstream differentiation into lymphoid lineages—including natural killer (NK), T, and B cells—using STEMdiffâ„¢ and StemSpanâ„¢ kits, all optimized for feeder-free workflows and scalable bioreactor formats.<br><br>As a supporter of, and participant in, ISSCR’s 2025 Annual Meeting, we share with you our presentation at ISSCR 2025. This presentation does not represent an endorsement from or support of the ISSCR. -
“Developing Regenerative Medicines†Featuring Dr. Stefan IrionOn this episode of the Stem Cell Podcast, Dr. Stefan Irion from BlueRock Therapeutics discusses the company’s Parkinson’s disease trial and the challenges of genetically manipulating stem cells. -
How to Scale Up and Differentiate hPSCs in 3D Suspension CultureJoin º£½ÇÆƽâ°æ scientists Tia Sojonky and Sarah McManus to learn all about hPSC scale-up and differentiation in 3D suspension culture. This webinar provides an in-depth look at advanced techniques for scaling up and differentiating hPSCs, with some practical tips for getting started and a 15-minute Q&A session that addresses some of the most pressing questions from the field. -
Tools for Optimizing Human Immune Cell ResearchObtaining consistent and reliable results when culturing immune cells can be challenging. Watch this webinar to discover how to obtain high yields of functional T cells, NK cells, B cells, dendritic cells, and macrophages for your research applications. The speaker, Evan Karas, also explains how to expand primary T cells without feeders or serum. -
“Translating Stem Cell Discoveries†Featuring Dr. Ilyas SingeçOn this episode of the Stem Cell Podcast, Dr. Ilyas Singeç from National Center for Advancing Translational Sciences discusses standardizing stem cell differentiation, high-throughput cell culture, personalized medicine, and the potential for biomanufacturing in space. -
Scaling Biomimetic Culture of Pluripotent Stem CellsHear from Dr. Maxime Feyeux, who discusses what the in vivo growth environment of pluripotent stem cells (PSCs) can teach us about in vitro culture. He summarizes some of the current challenges facing standard PSC culture technologies and shares a solution for mass producing high-quality PSCs for downstream applications. -
“Accelerating Stem Cell Treatments†Featuring Dr. Maria MillanOn this episode of the Stem Cell Podcast, Dr. Maria Millan from the California Institute for Regenerative Medicine (CIRM) talks about her transition from surgeon to stem cell specialist, how California culture has helped CIRM to thrive, and its role in training the next generation of stem cell scientists. -
“Laser-Based Cell Manipulation†Featuring Dr. Marinna MadridOn this episode of the Stem Cell Podcast, Dr. Marinna Madrid from Cellino discusses how lasers and image-guided machine learning can make iPSC-derived cell therapies viable at a large scale.
