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In this episode, co-hosts Drs. Nicole Quinn and Daylon James chat with Drs. Lisa Corwin and Sandhya Krishnan from the University of Colorado, Boulder. Dr. Corwin is an Associate Professor and Principal Investigator of the REACH Lab, which studies how early-career scientists engage with and persevere through challenges in their research. Dr. Krishnan is a NSF Postdoctoral Research Fellow, Postdoc Associate with FLAMEnet, and Project Lead at the Science of Failure. They talk about how students cope with research failures and how mentors can normalize and allow for failure on a smaller scale. They also talk about how researchers can be transparent with their experimental results.