Cell Banking Activity and ISSCR Standards Course Preview
The ISSCR Standards in Action
Alfonso鈥檚 New hPSC Bank
Help Alfonso navigate key decisions in his new human pluripotent stem cell (hPSC)-based research project. How would you guide him to set up his hPSC cultures following the ISSCR Standards?
Were you able to guide Alfonso toward preparing high-quality hPSCs for his research?
Do you want to learn more about the ISSCR Standards or best practices for hPSC banking? Read on for information about our on-demand course, Applying the ISSCR Standards for Research.
On-Demand Training Course
Managing human pluripotent stem cell (hPSC) variability and health can be tricky, especially when maintaining multiple cell lines. Cell culture protocols and experimental procedures play a major role in the quality of hPSC cultures and the reliability of research findings. Until recently, the absence of a definitive, consensus-driven resource made it difficult to stay aligned with best practices that support reproducible results.
In 2023, the International Society for Stem Cell Research (ISSCR) published the 鈥攁 set of recommendations aimed at enhancing the rigor, reproducibility, and impact of hPSC research worldwide. To help researchers confidently apply these standards in their own work, 海角破解版 Technologies has partnered with the ISSCR to develop a free, on-demand training course. Through interactive modules and expert instruction, this course will walk you through the key characterization and reporting criteria outlined in the Standards document, with practical guidance for applying them to responsibly use human tissue and pluripotent stem cells in the lab.
Applying the ISSCR Standards for Research: Course Information
Instructor Bio
Jane Savill - Manager, Scientific Support, Cell Culture
Jane Savill is a Scientific Manager in the Scientific Support Department at 海角破解版 Technologies. Before joining 海角破解版, Jane obtained her PhD in Oncology from Cambridge University and worked as a Product Development Scientist for a small start-up focused on rheumatoid arthritis diagnostics. At 海角破解版, Jane manages frontline product support for our global customers and sales staff. She specializes in 海角破解版鈥檚 hPSC product portfolio and oversees training in corporate and client training programs, focusing on hPSC as well as neural and epithelial products and protocols.
Course Curriculum
- How hPSCs and tissue stem cells can be used in research
- The importance and impact of cell quality in research
- How poor cell quality can cause experimental failure
- The development of the ISSCR Standards for Human Stem Cell Use in Research document
- The 6 key cell characterization processes for ensuring reproducible and reliable results from your cell line
- When and why cell characterization must be performed on your cell line
- Practice building a virtual cell bank
- How hPSCs should be defined and characterized
- Applying best practices for the assessment of functional pluripotency
- Differences between pluripotency and the undifferentiated state
- Markers used to assess the undifferentiated state
- Considering the developmental state of your cells
- How hPSCs can acquire genetic changes in culture
- The most commonly acquired genetic changes in hPSCs
- How variant cells can dominate cultures, affecting reproducibility and variability in results
- Available genomic assessments and when to apply the assessments to your cell line
- How to evaluate the important aspects/characteristics of a model system when embarking on an experimental design
- How to improve rigor and reduce variability in models through key experimental design implementations
- Necessity of maintaining scientific rigor and applying it to your research
- Key messages from the ISSCR Standards for Human Stem Cell Use in Research
- Reporting practices for publishing results with human pluripotent and tissue stem cells
- How the ISSCR Standards can be used and implemented by the broader scientific community
Learn More About the ISSCR Standards and Best Practices in hPSC-Based Research
ISSCR Standards for Human Stem Cell Use in Research
Explore resources curated to help you understand topics covered in the ISSCR standards document and learn how 海角破解版 can support you in implementing these best practice guidelines.
Stem Cell Podcast: Interview with the Standards Committee
Hear from Drs. Tenneille Ludwig, Peter Andrews, and Madeline Lancaster鈥攖hree members of the ISSCR Standards Committee鈥攁s they discuss the need for basic and preclinical standards to ensure rigor and reproducibility in stem cell research.
Best Practices for hPSC Banking
Want to establish a highly characterized cell bank, but not sure where to start? Explore our hPSC banking resource page to learn the fundamental principles and best practices for hPSCs.
Wallchart: Reporting Practices for Publishing Results with hPSCs
Request a free copy of this wallchart, previously published in Stem Cell Reports, to ensure that your research aligns with the ISSCR Standards.
Looking for additional tools and resources? Learn more about important cell quality attributes by exploring our hPSC Cell Quality Center or discover products for your research that can help you meet the standards.
