Essential Knowledge Briefing: Genome Editing Applications for Disease Modeling and Cell Therapy
Get Started with CRISPR: From System Selection to Experimental Success
CRISPR-Cas systems have become essential tools in cell biology, enabling the precise and efficient genetic manipulation of mammalian cells. Through targeted modification of specific genes or regulatory regions, researchers can rapidly generate accurate genetic models to investigate both normal and disease-related cellular processes. In addition to their widespread use in basic research, CRISPR-based genome editing continues to show promise in therapeutic development.
This e-book offers an overview for researchers new to CRISPR or exploring its use in future experiments.
In this e-book you will find:
- A brief history of precise genome editing techniques, including CRISPR
- Guidance for choosing the right CRISPR system for your experiment
- Applications for CRISPR-Cas technology in culture systems
- Current challenges and troubleshooting
- Future directions of the field
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